10, 11, 12, 13, 14ĭespite the increase in clinical and social interest in narcolepsy during recent decades, 15 epidemiological data on narcolepsy are sparse in South Korea. The incidence rate of narcolepsy before the 2009 H1N1 pandemic was approximately 1/100,000 persons per year, with the peak of onset in persons aged 10–20 years, 7 and a 2- to 25-fold increase in incidence in children and adolescents was reported following the H1N1 pandemic between 20 in European countries and China. 3 The incidence of narcolepsy was less studied than the prevalence before the H1N1 influenza pandemic in 2009, but numerous observational studies have investigated the changes in narcolepsy type 1 incidence after this pandemic or in association with H1N1 vaccination. 5, 6, 7, 8, 9 Among Asian countries, a study conducted in Hong Kong that used telephone interviews, polysomnography (PSG), and human leukocyte antigen (HLA) typing found a prevalence of 34/100,000 persons. 1, 4 Previous studies involving general populations found that the prevalence of narcolepsy was 20–50/100,000 persons in North America and Europe. 1, 2, 3 It is characterized by excessive daytime sleepiness and cataplexy, as well sleep-related symptoms including hypnagogic hallucinations, sleep paralysis, and disturbed nighttime sleep. Narcolepsy is a chronic neurological disorder associated with significant physical and psychosocial impairments.
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